In tribute to Corwin Hansch, father of QSAR

In tribute to Corwin Hansch, father of QSAR

In this issue of Journal of Computer-Aided Molecular Design we pay tribute to Corwin Hansch, who died on May 8 at the age of 91. Professor Hansch (Corwin to almost everyone, at his insistence) was a giant in our field, the ‘father’ of QSAR, and the vanguard of rational drug design. Thanks to his long-time colleague and coworker, Cynthia Selassie, also of Pomona College, we are, with sadness, pu...

QSAR : Hansch Analysis and Related Approaches

From Hansch-Fujita Analysis to AFMoC: A Road to Structure-Based QSAR.

Since the pioneering effort of Hansch and Fujita, quantitative structure-activity relationships (QSAR) have proved valuable in optimizing lead structures. Enriching classical 3D-QSAR analysis, which exploits the three-dimensional structure of ligands, with structural information of the target has helped to improve the interpretability of the derived models and to increase their predictive power...

Morris F. Collen at 100: a tribute to "the father of medical informatics".

This editorial is dedicated affectionately to Morris F. Collen, MD, “the father of Medical Informatics”, on the occasion of his 100th birthday, November 12, (1913 –2013). Serving for 30 years, from 1970 to 1999, on the Editorial Board of Methods of Information in Medicine, Dr. Collen is on rank 6 on the list of persons contributing the longest to this journal [1]. It is also the occasion to cel...

A Tribute to Peter H Seeburg (1944–2016): A Founding Father of Molecular Neurobiology

On 22nd August 2016, the fields of molecular neurobiology and endocrinology lost one of their pioneers and true giants, Peter Seeburg, who died aged 72, a day after his birthday. His funeral ceremony took place in Heidelberg where he had worked since 1988, first as a professor at the University of Heidelberg (ZMBH) and then since 1996 as a director of the Max Plank Institute (Department of Mole...